 Standings at start of day | Results for July 18, 1888 Game 221: Sioux City 4, Des Moines 3 |
| Game 221: Sioux City @ Des Moines Sioux City 4, Des Moines 3 Sioux City Journal  | Game 222: Milwaukee @ Minneapolis Minneapolis 7, Milwaukee 5 Minneapolis Star Tribune  | Game 223: Kansas City @ Omaha Kansas City 6, Omaha 3 Omaha Daily Bee  | Game 224: Chicago @ St. Paul Chicago 4, St. Paul 3 St. Paul Globe  |